The York Research Database

The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy

Seed, R. I., Taurozzi, A. J., Wilcock, D. J., Nappo, G., Erb, H. H. H., Read, M. L., Gurney, M., Archer, L. K., Ito, S., Rumsby, M. G., Petrie, J. L., Clayton, A., Maitland, N. J. & Collins, A. T., 26 Mar 2019

Article in Scientific Reports

Spontaneous development of Epstein-Barr Virus associated human lymphomas in a prostate cancer xenograft program

Taurozzi, A. J., Beekharry, R., Wantoch, M., Labarthe, M-C., Walker, H. F., Seed, R. I., Simms, M. S., Rodrigues, G., Bradford, J., van der Horst, G., van der Pluijm, G. & Collins, A. T., 16 Nov 2017

Article in PLoS ONE

Selective targeting of TGF-β activation to treat fibroinflammatory airway disease

Minagawa, S., Lou, J., Seed, R. I., Cormier, A., Wu, S., Cheng, Y., Murray, L., Tsui, P., Connor, J., Herbst, R., Govaerts, C., Barker, T., Cambier, S., Yanagisawa, H., Goodsell, A., Hashimoto, M., Brand, O. J., Cheng, R., Ma, R., McKnelly, K. J. & 12 others, Wen, W., Hill, A., Jablons, D., Wolters, P., Kitamura, H., Araya, J., Barczak, A. J., Erle, D. J., Reichardt, L. F., Marks, J. D., Baron, J. L. & Nishimura, S. L., 18 Jun 2014

Article in Science Translational Medicine

The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells

Read, M. L., Seed, R. I., Fong, J. C. W., Modasia, B., Ryan, G. A., Watkins, R. J., Gagliano, T., Smith, V. E., Stratford, A. L., Kwan, P. K., Sharma, N., Dixon, O. M., Watkinson, J. C., Boelaert, K., Franklyn, J. A., Turnell, A. S. & McCabe, C. J., Apr 2014

Article in Endocrinology

Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells

Lewy, G. D., Ryan, G. A., Read, M. L., Fong, J. C. W., Poole, V., Seed, R. I., Sharma, N., Smith, V. E., Kwan, P. P. K., Stewart, S. L., Bacon, A., Warfield, A., Franklyn, J. A., McCabe, C. J. & Boelaert, K., 1 Nov 2013

Article in Clinical endocrinology

PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8

Smith, V. E., Read, M. L., Turnell, A. S., Sharma, N., Lewy, G. D., Fong, J. C. W., Seed, R. I., Kwan, P., Ryan, G., Mehanna, H., Chan, S. Y., Darras, V. M., Boelaert, K., Franklyn, J. A. & McCabe, C. J., Jul 2012

Article in Clinical endocrinology

Adenovirus E4orf3 targets transcriptional intermediary factor 1γ for proteasome-dependent degradation during infection

Forrester, N. A., Patel, R. N., Speiseder, T., Groitl, P., Sedgwick, G. G., Shimwell, N. J., Seed, R. I., Catnaigh, P. Ó., McCabe, C. J., Stewart, G. S., Dobner, T., Grand, R. J. A., Martin, A. & Turnell, A. S., Mar 2012

Article in JOURNAL OF VIROLOGY

Proto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatment

Read, M. L., Lewy, G. D., Fong, J. C. W., Sharma, N., Seed, R. I., Smith, V. E., Gentilin, E., Warfield, A., Eggo, M. C., Knauf, J. A., Leadbeater, W. E., Watkinson, J. C., Franklyn, J. A., Boelaert, K. & McCabe, C. J., 1 Oct 2011

Article in Cancer research